PubSort

Pubsort is a free search engine for publications that pre-summarizes each paper’s key findings, hypothesis, conclusion, and supporting evidence.

Built and maintained by Alan Cheng

Recent Publications

Study on Factors Affecting Lymph Node Metastasis in Oesophageal Cancer

Department of Surgery and Surgical Basic Science, Graduate School of Medicine, Kyoto University 1999 n=308 publication

Sato F, Shimada Y, Watanabe G, Uchida S, Makino T, Imamura M

Title

Study on Factors Affecting Lymph Node Metastasis in Oesophageal Cancer

Hypothesis

Does the expression of VEGF, MMP-9, and E-cadherin change during lymph node metastasis in oesophageal cancer?

Conclusion

The expression of VEGF, MMP-9, and E-cadherin changes during the process of lymph node metastasis in oesophageal cancer, with different patterns of change.

Behavior Change in Perinatal Care Practices in Nepal

Institute of Child Health, University College London 2006 n=5400 publication 10 minutes Evidence: high

Wade Angie, Osrin David, Shrestha Bhim Prasad, Sen Aman, Morrison Joanna, Tumbahangphe Kirti Man, Manandhar Dharma S, de L Costello Anthony M

Title

Behavior Change in Perinatal Care Practices in Nepal

Hypothesis

The study aims to determine the mechanisms via which a women's group intervention affects perinatal care practices among rural women.

Conclusion

Women's groups significantly improved perinatal care behaviors among women who were not previously following good practices.

Genetic Changes in Brain Tumors

Wessex Regional Genetics Laboratory, Salisbury, Wiltshire, UK 1999 n=37 publication Evidence: moderate

Nicholson J C, Ross F M, Kohler J A, Ellison D W

Title

Genetic Changes in Brain Tumors

Hypothesis

Chromosomal imbalances in central nervous system primitive neuroectodermal tumours (PNETs) reflect site and histology.

Conclusion

The study found significant associations between tumour variants and genetic abnormalities in medulloblastomas.

Increased Risk of Myositis Autoantibodies After COVID-19 Vaccination

Hospital Clínico San Carlos, Madrid, Spain 2024 n=788 publication 10 minutes Evidence: moderate

García-Bravo Laura, Prada Alvaro, Gutiérrez Larrañaga María, Espinosa Ros Eduardo, Almeida González Delia, Martín Martínez Dolores, Rodríguez Sánchez Telesforo, Mingorance Gámez Carlos Gustavo, Jurado Roger Aurora, Aguado Álvarez Rocío, Díaz Luna María De Las Mercedes, Rodríguez Hernández Carmen, de la Varga-Martínez Raquel, López-Cueto María, Julià Benique Maria Rosa, San José-Cascón Miriam, Quirant-Sánchez Bibiana, Martínez-Chamorro Alba, Marcaida-Benito Goitzane, Timoneda Timoneda Pilar Teresa, Fandos Sánchez Marta, Sacristán Enciso Beatriz, Mohamed Mohamed Kauzar, Guerra-Galán Teresa, Villegas Ángela, Roncancio-Clavijo Andrés, Rodríguez-Mahou Margarita, Sánchez-Ramón Silvia, Fernández-Arquero Miguel, Candelas-Rodríguez Gloria, Ochoa-Grullón Juliana

Title

Increased Risk of Myositis Autoantibodies After COVID-19 Vaccination

Hypothesis

This study aimed to describe the incidence of idiopathic inflammatory myopathies (IIM) following SARS-CoV-2 infection or vaccination and compare rates between exposures.

Conclusion

The study found distinct patterns of myositis autoantibodies associated with SARS-CoV-2 infection and vaccination, indicating increased autoimmune risks.

Malaria and Trypanosome Transmission: Different Parasites, Same Rules?

University of Edinburgh 2011 publication Evidence: moderate

Laura C. Pollitt, Paula MacGregor, Keith Matthews, Sarah E. Reece

Title

Malaria and Trypanosome Transmission: Different Parasites, Same Rules?

Hypothesis

How do parasites trade-off investment in survival and transmission in response to variation in the within-host environment?

Conclusion

The study suggests that evolutionary theory can explain the investment strategies of trypanosomes, similar to those observed in malaria parasites.

Infections and Childhood Leukaemia Risk

Childhood Cancer Research Group, University of Oxford 1999 n=131 publication Evidence: moderate

Dockerty J D, Skegg D C G, Elwood J M, Herbison G P, Becroft D M O, Lewis M E

Title

Infections and Childhood Leukaemia Risk

Hypothesis

What is the role of infections in the aetiology of childhood leukaemia?

Conclusion

The study found an increased risk of leukaemia associated with reported influenza infection during the first year of life.

Plasmodium Species in Wild Apes and Their Implications for Human Infection

Wellcome Trust Sanger Institute 2011 n=3000 publication 10 minutes Evidence: moderate

Rayner Julian C., Liu Weimin, Peeters Martine, Sharp Paul M., Hahn Beatrice H.

Title

Plasmodium Species in Wild Apes and Their Implications for Human Infection

Hypothesis

Could wild apes be a source of Plasmodium infections in humans?

Conclusion

The study suggests that wild apes harbor multiple Plasmodium species, which may pose a risk for future cross-species transmissions to humans.

Cancer Therapy-Related Cardiac Dysfunction: A Review of Current Trends

1st Department of Cardiology, Hippokration General Hospital, National and Kapodistrian University of Athens, Greece 2024 publication Evidence: moderate

Theofilis Panagiotis, Vlachakis Panayotis K., Oikonomou Evangelos, Drakopoulou Maria, Karakasis Paschalis, Apostolos Anastasios, Pamporis Konstantinos, Tsioufis Konstantinos, Tousoulis Dimitris

Title

Cancer Therapy-Related Cardiac Dysfunction: A Review of Current Trends

Hypothesis

How do cancer therapies impact cardiac health?

Conclusion

The review highlights the importance of early detection and interdisciplinary collaboration in managing cancer therapy-related cardiac dysfunction.

Improving Chemotherapy with Tumor pH Manipulation

Arizona Cancer Center 1999 publication Evidence: moderate

Raghunand N, He X, Sluis R van, Mahoney B, Baggett B, Taylor C W, Paine-Murrieta G, Roe D, Bhujwalla Z M, Gillies R J

Title

Improving Chemotherapy with Tumor pH Manipulation

Hypothesis

Can manipulating the pH of tumors enhance the effectiveness of chemotherapy drugs like doxorubicin?

Conclusion

Raising the pH of tumors with sodium bicarbonate significantly improves the effectiveness of doxorubicin in treating breast cancer.

Improving Heart Cell Integration with Connexin 43

Imperial College London 2006 publication Evidence: moderate

Tolmachov Oleg, Ma Yu-Ling, Themis Michael, Patel Pravina, Spohr Hilmar, MacLeod Kenneth T, Ullrich Nina D, Kienast Yvonne, Coutelle Charles, Peters Nicholas S

Title

Improving Heart Cell Integration with Connexin 43

Hypothesis

Can overexpression of connexin 43 in skeletal myoblasts enhance their electrical integration with cardiac myocytes?

Conclusion

Overexpression of connexin 43 in skeletal myoblasts improves their electrical coupling with cardiac myocytes.

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