A plethora of Plasmodium species in wild apes: a source of human infection?
2011

Plasmodium Species in Wild Apes and Their Implications for Human Infection

Sample size: 3000 publication 10 minutes Evidence: moderate

Author Information

Author(s): Rayner Julian C., Liu Weimin, Peeters Martine, Sharp Paul M., Hahn Beatrice H.

Primary Institution: Wellcome Trust Sanger Institute

Hypothesis

Could wild apes be a source of Plasmodium infections in humans?

Conclusion

The study suggests that wild apes harbor multiple Plasmodium species, which may pose a risk for future cross-species transmissions to humans.

Supporting Evidence

  • Recent studies have uncovered numerous new Plasmodium species in wild apes.
  • Some ape Plasmodium species are closely related to human malaria parasites.
  • High prevalence rates of Laverania parasites were found in chimpanzees and western gorillas.

Takeaway

Scientists found many types of malaria parasites in wild apes, which could make people sick if they get infected.

Methodology

The study used non-invasive methods to analyze nearly 3,000 fecal samples from wild apes across Africa.

Limitations

The study's findings are based on fecal samples, which may not capture all infections, and the high frequency of mixed-species infections complicates the analysis.

Participant Demographics

Wild-living apes from multiple sites across Africa.

Digital Object Identifier (DOI)

10.1016/j.pt.2011.01.006

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