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Comparing Surgery and Infliximab for Crohn's Disease

Academic Medical Center, Amsterdam, The Netherlands 2008 n=130 publication Evidence: moderate

Eshuis Emma J, Bemelman Willem A, van Bodegraven Ad A, Sprangers Mirjam AG, Bossuyt Patrick MM, de Wit AW Marc van Milligen, Crolla Rogier MPH, Cahen Djuna L, Oostenbrug Liekele E, Sosef Meindert N, Voorburg Annet MCJ, Davids Paul HP, van der Woude C Janneke, Lange Johan, Mallant Rosalie C, Boom Maarten J, Lieverse Rob J, van der Zaag Edwin S, Houben Martin HMG, Vecht Juda, Pierik Robert EGJM, van Ditzhuijsen Theo JM, Prins Hubert A, Marsman Willem A, Stockmann Henricus B, Brink Menno A, Consten Esther CJ, van der Werf Sjoerd DJ, Marinelli Andreas WKS, Jansen Jeroen M, Gerhards Michael F, Bolwerk Clemens JM, Stassen Laurents PS, Spanier BW Marcel, Bilgen Ernst Jan Spillenaar, van Berkel Anne-Marie, Cense Huib A, van Heukelem Henk A, van de Laar Arnold, Slot Warner Bruins, Eijsbouts Quirijn A, van Ooteghem Nancy AM, van Wagensveld Bart, van den Brande Jan MH, van Geloven Anna AW, Bruin Karien F, Maring John K, Oldenburg Bas, van Hillegersberg Richard, de Jong Dirk J, Bleichrodt Robert, van der Peet Donald L, Dekkers Pascal EP, Goei T Hauwy, Stokkers Pieter CF

Title

Comparing Surgery and Infliximab for Crohn's Disease

Hypothesis

Is laparoscopic ileocolic resection more effective than infliximab treatment for recurrent Crohn's disease of the distal ileum?

Conclusion

The study aims to determine whether infliximab treatment or surgery is the better option for patients with recurrent distal ileitis in Crohn's disease.

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