PubSort

Pubsort is a free search engine for publications that pre-summarizes each paper’s key findings, hypothesis, conclusion, and supporting evidence.

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Recent Publications

Identifying Genes Affecting Bone Mineral Density and Fracture Risk

University of Queensland Diamantina Institute 2011 n=2036 publication 10 minutes Evidence: high

Duncan Emma L., Danoy Patrick, Kemp John P., Leo Paul J., McCloskey Eugene, Nicholson Geoffrey C., Eastell Richard, Prince Richard L., Eisman John A., Jones Graeme, Sambrook Philip N., Reid Ian R., Dennison Elaine M., Wark John, Richards J. Brent, Uitterlinden Andre G., Spector Tim D., Esapa Chris, Cox Roger D., Brown Steve D. M., Thakker Rajesh V., Addison Kathryn A., Bradbury Linda A., Center Jacqueline R., Cooper Cyrus, Cremin Catherine, Estrada Karol, Felsenberg Dieter, Glüer Claus-C., Hadler Johanna, Henry Margaret J., Hofman Albert, Kotowicz Mark A., Makovey Joanna, Nguyen Sing C., Nguyen Tuan V., Pasco Julie A., Pryce Karena, Reid David M., Rivadeneira Fernando, Roux Christian, Stefansson Kari, Styrkarsdottir Unnur, Thorleifsson Gudmar, Tichawangana Rumbidzai, Evans David M., Brown Matthew A.

Title

Identifying Genes Affecting Bone Mineral Density and Fracture Risk

Hypothesis

Can a genome-wide association study identify novel genes associated with bone mineral density and fracture risk in postmenopausal women?

Conclusion

The study identified six new genetic associations with bone mineral density and confirmed the efficiency of extreme-truncate selection designs for such studies.

VEGF-A and PAIP2 in Head and Neck Cancer

Institute of Signalling, Developmental Biology and Cancer Research, CNRS – UMR 6543, University of Nice Sophia-Antipolis 2006 n=54 publication 10 minutes Evidence: high

Onesto C, Hannoun-Lévi J-M, Chamorey E, Formento J-L, Ramaioli A, Pagès G

Title

VEGF-A and PAIP2 in Head and Neck Cancer

Hypothesis

Is there a correlation between VEGF-A and PAIP2 expression in head and neck squamous cell carcinomas (HNSCC)?

Conclusion

VEGF-A expression is a significant prognostic marker in head and neck cancer, while PAIP2 does not correlate with patient outcomes.

Autoantibodies in Hospitalized Patients with COVID-19

Johns Hopkins University School of Medicine 2024 n=118 publication 10 minutes Evidence: moderate

E Tiniakou, L Casciola-Rosen, Mekha A Thomas, Y Manabe, Annukka AR Antar, M Damarla, P M Hassoun, L Gao, Z Wang, S Zeger, A Rosen

Title

Autoantibodies in Hospitalized Patients with COVID-19

Hypothesis

Do patients hospitalized with COVID-19 develop autoantibodies against CD209 and CD209L receptors?

Conclusion

IgM autoantibodies against CD209 and CD209L were found in hospitalized COVID-19 patients, but these were not associated with disease severity.

ATM Gene and Breast Cancer Risk in Jewish Women

The Danek Gertner Institute of Human Genetics, Tel-Hashomer, Israel 2006 n=260 publication 10 minutes Evidence: high

Koren M, Kimmel G, Ben-Asher E, Gal I, Papa M Z, Beckmann J S, Lancet D, Shamir R, Friedman E

Title

ATM Gene and Breast Cancer Risk in Jewish Women

Hypothesis

Does the ATM gene contribute to breast cancer risk in high-risk Jewish women?

Conclusion

A specific ATM SNP and haplotype are associated with increased breast cancer risk in high-risk non-Ashkenazi Jews.

Pediatric Brugada Syndrome: Understanding Fever's Role

Hong Kong Children's Hospital 2024 n=8 publication Evidence: low

Leung Hei‐To, Kwok Sit‐Yee, Shih Fong‐Ying, Lun Kin‐Shing, Yung Tak‐Cheung, Tsao Sabrina

Title

Pediatric Brugada Syndrome: Understanding Fever's Role

Hypothesis

This study investigates the clinical and genetic characteristics of children with Brugada syndrome in Hong Kong.

Conclusion

Fever plays a significant role in unmasking Brugada syndrome in children, and asymptomatic children managed conservatively have a favorable prognosis.

Understanding Epigenetic Regulation in Human Mammary Epithelial Cells

Dana-Farber Cancer Institute 2011 n=3 publication 10 minutes Evidence: high

Maruyama Reo, Choudhury Sibgat, Kowalczyk Adam, Bessarabova Marina, Beresford-Smith Bryan, Conway Thomas, Kaspi Antony, Wu Zhenhua, Nikolskaya Tatiana, Merino Vanessa F., Lo Pang-Kuo, Liu X. Shirley, Nikolsky Yuri, Sukumar Saraswati, Haviv Izhak, Polyak Kornelia

Title

Understanding Epigenetic Regulation in Human Mammary Epithelial Cells

Hypothesis

The study investigates the epigenetic mechanisms regulating cell type-specific gene expression in human mammary epithelial cells.

Conclusion

The research identifies significant differences in histone and DNA methylation patterns between progenitor and luminal epithelial cells, suggesting distinct regulatory mechanisms for gene expression.

Radiochemotherapy in Stage III/IV Head and Neck Cancer

Department of Radiooncology, University of Regensburg Hospital 2006 n=200 publication Evidence: low

Schäfer C, Dietl B, Kölbl O

Title

Radiochemotherapy in Stage III/IV Head and Neck Cancer

Conclusion

The study suggests that combined radiochemotherapy may lead to inferior outcomes compared to adjuvant radiotherapy, despite not reaching statistical significance.

New Electrolyte for Longer Lasting Lithium-Ion Batteries

Harbin Institute of Technology 2024 publication 10 minutes Evidence: high

Dong Shengwei, Shi Lingfeng, Geng Shenglu, Ning Yanbin, Kang Cong, Zhang Yan, Liu Ziwei, Zhu Jiaming, Qiang Zhuomin, Zhou Lin, Yin Geping, Li Dalong, Mu Tiansheng, Lou Shuaifeng

Title

New Electrolyte for Longer Lasting Lithium-Ion Batteries

Hypothesis

Can a new deep eutectic electrolyte improve the cycling stability of silicon oxide anodes in lithium-ion batteries?

Conclusion

The new succinonitrile-based electrolyte significantly enhances the cycling stability of silicon oxide anodes by creating a more stable solid electrolyte interphase.

African Ancestry in Southern Europeans, Levantines, and Jews

Harvard Medical School 2011 n=6529 publication Evidence: high

Moorjani Priya, Patterson Nick, Hirschhorn Joel N., Keinan Alon, Hao Li, Atzmon Gil, Burns Edward, Ostrer Harry, Price Alkes L., Reich David

Title

African Ancestry in Southern Europeans, Levantines, and Jews

Hypothesis

What is the proportion and date of African gene flow into West Eurasian populations?

Conclusion

Southern Europeans have inherited 1%–3% African ancestry, Levantines 4%–15%, and Jewish populations 3%–5%, with mixture dates ranging from about 32 to 72 generations ago.

Correction on Neoadjuvant Chemotherapy in Breast Cancer

Cancer Research UK 2006 publication

Manton D J, Chaturvedi A, Hubbard A, Lind M J, Lowry M, Maraveyas A, Pickles M D, Tozer D J, Turnbull L W

Title

Correction on Neoadjuvant Chemotherapy in Breast Cancer

Conclusion

The units for the apparent diffusion coefficient (ADC) data were incorrectly quoted in the original paper.

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