A Tale of Two Conditions: Pediatric Brugada Syndrome Unveiled—Navigating the Challenges of Coexisting Arrhythmia and Fever‐Induced ECG Pattern
2024

Pediatric Brugada Syndrome: Understanding Fever's Role

Sample size: 8 publication Evidence: low

Author Information

Author(s): Leung Hei‐To, Kwok Sit‐Yee, Shih Fong‐Ying, Lun Kin‐Shing, Yung Tak‐Cheung, Tsao Sabrina

Primary Institution: Hong Kong Children's Hospital

Hypothesis

This study investigates the clinical and genetic characteristics of children with Brugada syndrome in Hong Kong.

Conclusion

Fever plays a significant role in unmasking Brugada syndrome in children, and asymptomatic children managed conservatively have a favorable prognosis.

Supporting Evidence

  • Seven out of eight patients had fever at initial presentation.
  • 62.5% of asymptomatic patients were diagnosed during febrile illness.
  • All symptomatic patients received implantable cardioverter-defibrillator placement.

Takeaway

Fever can reveal a heart condition called Brugada syndrome in kids, but if they don't have symptoms, they usually do well with simple care.

Methodology

A retrospective review of pediatric Brugada syndrome patients under 18 years old at a tertiary pediatric cardiology center from 2002 to 2022.

Limitations

The study is limited by its small sample size and retrospective design.

Participant Demographics

The cohort consisted of 8 pediatric patients, predominantly male (6 boys and 2 girls), with a mean age of 10 years.

Digital Object Identifier (DOI)

10.1111/anec.70009

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