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Study of Genes Related to Lung Function

University Hospital of Nottingham, Nottingham, United Kingdom 2011 n=20288 publication Evidence: low

Obeidat Ma'en, Wain Louise V., Shrine Nick, Kalsheker Noor, Artigas Maria Soler, Repapi Emmanouela, Burton Paul R., Johnson Toby, Ramasamy Adaikalavan, Zhao Jing Hua, Zhai Guangju, Huffman Jennifer E., Vitart Veronique, Albrecht Eva, Igl Wilmar, Hartikainen Anna-Liisa, Pouta Anneli, Cadby Gemma, Hui Jennie, Palmer Lyle J., Hadley David, McArdle Wendy L., Rudnicka Alicja R., Barroso Inês, Loos Ruth J. F., Wareham Nicholas J., Mangino Massimo, Soranzo Nicole, Spector Tim D., Gläser Sven, Homuth Georg, Völzke Henry, Deloukas Panos, Granell Raquel, Henderson John, Grkovic Ivica, Jankovic Stipan, Zgaga Lina, Polašek Ozren, Rudan Igor, Wright Alan F., Campbell Harry, Wild Sarah H., Wilson James F., Heinrich Joachim, Imboden Medea, Probst-Hensch Nicole M., Gyllensten Ulf, Johansson Åsa, Zaboli Ghazal, Mustelin Linda, Rantanen Taina, Surakka Ida, Kaprio Jaakko, Jarvelin Marjo-Riitta, Hayward Caroline, Evans David M., Koch Beate, Musk Arthur William, Elliott Paul, Strachan David P., Tobin Martin D., Sayers Ian, Hall Ian P., Consortium SpiroMeta

Title

Study of Genes Related to Lung Function

Hypothesis

Are single nucleotide polymorphisms (SNPs) in previously reported genetic regions associated with lung function in a large population sample?

Conclusion

The study found no strong evidence for association between previously reported lung function genes and lung function measures in the general population.

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