PubSort

Pubsort is a free search engine for publications that pre-summarizes each paper’s key findings, hypothesis, conclusion, and supporting evidence.

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Recent Publications

Improving SNP Association Studies with Haplotype Block Partitioning

European Academy, Bolzano, Italy 2008 n=45 publication Evidence: high

Pattaro Cristian, Ruczinski Ingo, Fallin Danièle M, Parmigiani Giovanni

Title

Improving SNP Association Studies with Haplotype Block Partitioning

Hypothesis

Can haplotype block partitioning improve the identification of disease-related SNPs in association studies?

Conclusion

The study shows that the MATILDE method for block partitioning is more efficient than existing methods in identifying disease loci.

Interleukin-2 Receptor and Ovarian Cancer

Glasgow Royal Infirmary 1993 n=78 publication Evidence: moderate

O.J. Owens, C. Taggart, R. Wilson, J.J. Walker, J.H. McKillop, J.H. Kennedy

Title

Interleukin-2 Receptor and Ovarian Cancer

Hypothesis

The study investigates whether serum levels of interleukin-2 receptor (IL-2R) can differentiate between malignant and benign ovarian tumors.

Conclusion

Serum IL-2R levels are significantly elevated in patients with malignant ovarian tumors compared to both normal controls and benign ovarian tumors.

First Human Study of Stem Cell-Derived Corneal Transplant

Department of Ophthalmology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan 2024 n=4 publication Evidence: low

Soma Takeshi MD, Oie Yoshinori MD, Takayanagi Hiroshi MS, Matsubara Shoko BA, Yamada Tomomi PhD, Nomura Masaki PhD, Yoshinaga Yu MD, Maruyama Kazuichi MD, Watanabe Atsushi MD, Takashima Kayo PhD, Mao Zaixing PhD, Quantock Andrew J Prof PhD, Hayashi Ryuhei PhD, Nishida Kohji Prof MD

Title

First Human Study of Stem Cell-Derived Corneal Transplant

Hypothesis

Can induced pluripotent stem cell-derived corneal epithelial cell sheets effectively treat limbal stem cell deficiency in humans?

Conclusion

The transplantation of stem cell-derived corneal epithelial cell sheets was found to be safe and showed positive clinical outcomes in all patients over a two-year period.

Predicting Alzheimer's Disease from Mild Cognitive Impairment

University of Newcastle 2011 n=350 publication 10 minutes Evidence: moderate

Cui Yue, Liu Bing, Luo Suhuai, Zhen Xiantong, Fan Ming, Liu Tao, Zhu Wanlin, Park Mira, Jiang Tianzi, Jin Jesse S.

Title

Predicting Alzheimer's Disease from Mild Cognitive Impairment

Hypothesis

The combination of different modes of data would achieve better results in predicting conversion from MCI to AD.

Conclusion

The study established meaningful multivariate predictors that may be useful for clinical diagnosis of Alzheimer's disease.

Monitoring Salicylic Acid and Acetylsalicylic Acid in Pharmaceuticals

University of Córdoba 1990 publication Evidence: moderate

j. M. L6pez Fernindez, M. D. Luque de Castro, M. Valcircel

Title

Monitoring Salicylic Acid and Acetylsalicylic Acid in Pharmaceuticals

Hypothesis

Can a new FIA manifold effectively determine salicylic acid and acetylsalicylic acid simultaneously in pharmaceutical preparations?

Conclusion

The study demonstrates that the FIA method can successfully monitor the dissolution of aspirin tablets by determining both salicylic acid and acetylsalicylic acid.

A New Model for Breast Cancer Research

Goodwin Institute for Cancer Research, Inc. 1993 n=10 publication Evidence: moderate

J. Hurst, N. Maniar, J. Tombarkiewicz, F. Lucas, C. Roberson, Z. Steplewski, W. James, J. Perras

Title

A New Model for Breast Cancer Research

Hypothesis

Can a human breast tumor xenograft line be developed that metastasizes in a mouse model?

Conclusion

The GI-101 xenograft line consistently metastasizes to the lungs of athymic mice, providing a unique model for studying breast cancer metastasis.

Source of Previous Treatment for Re-Treatment TB Cases in India

Central TB Division, Directorate General of Health Services, Ministry of Health and Family Welfare, Government of India 2011 n=1712 publication Evidence: moderate

Sachdeva Kuldeep Singh, Satyanarayana Srinath, Dewan Puneet Kumar, Nair Sreenivas Achuthan, Reddy Raveendra, Kundu Debasish, Chadha Sarabjit Singh, Madhugiri Venkatachalaiah Ajay Kumar, Parmar Malik, Chauhan Lakhbir Singh

Title

Source of Previous Treatment for Re-Treatment TB Cases in India

Hypothesis

What is the source of previous treatment for re-treatment TB patients registered under India's Revised National TB Control Programme?

Conclusion

Nearly half of the re-treatment TB cases registered with the national programme were most recently treated outside the programme setting.

Cell Cycle Control and Cancer Research Meeting Report

1993 publication

S. Moreno, R. Bartlett, S. Sazer, P. Nurse, G.F. Vande Woude, N. Shulz, R. Zhou, W. Matten, K. Fukasawa, N. Yew, M. Oskarrson, D.M. Livingstone, E. Harlow, L. Cao, A. Fattaey, K. Helin, M.-H. Lee, J. Lees, A. Tallis, M. Vidal, L. Yamasaki, L. Zhu, N. Dyson, D.P. Lane, G. Peters, G.A. Lammie, S. Bates, I. Palmero, L. Bonetta, C. Dickson, K.H. Vousden, R. Davies, T. Crook, S.J. Falk, P.J. Smith, P.W.M. Johnson, S.M. Watt, D.R. Betts, D. Davies, T.A. Lister, J.S. Beesley, W.P. Soutter, J.O. White, H. Warenius, P. Browning, M. Hola, S. Castleden, A. O'Toole, M. Howard, R.F. Brooks, L.G. Bobrow, L.C. Happerfield, R.J. Springall, R.R. Millis, S.J. Oakes, P.D. Stanton, T.G. Cooke, N. Pendleton, G.R. Dixon, N.L. Occleston, H.E. Burnett, M.W. Myskow, J.A. Green, P. Carnochan, B.J. Deehan, M. Trivedi, A.J. Tombs, J. Sandle, R.J. Ott, M.C.M. Finnegan, K.A. Lee, D.W. Hammond, J.R. Geopel, B.W. Hancock, M.H. Goyns, R. Brown, A. Edlin, P. Burns, C. Clugston, B. Vojtesek, D.M. Barnes, E.A. Dublin, C.J. Fisher, D.A. Levison, R.R. Millis, N.S.B. Thomas, A. Bybee, S.M. Phillips, D. Morton, S.J. Lee, D.M. Wallace, J.P. Neoptolemos, V. Makinde, S. Dilly, C. Corbishley, S. Lowndes, J. Quilliamm, R. Sutcliffe, H. Ford, J.-C. Gazet, J. MacCallum, J.C. Keen, J.M.S. Bartlett, A.M. Thompson, W.R. Miller, J.M. Dixon, J.H.R. Winstanley, S. Anandappa, D. Fernig, S.J. Leinster, P.S. Rudland, B.R. Barraclough, R. Hoffman, D. Paper, D.A. Browell, J.A. Kirby, B.K. Shenton, T.W.J. Lennard, A.M. Abbasi, K.A. Chester, I.C. Talbot, G. Boxer, R.H.J. Begent, D.W. Miles, B. Davies, L.C. Happerfield, L.G. Bobrow, R.D. Rubens, F.R. Balkwill, H. Wasan, T. Baker, S. Tickle, A. Docherty, J. Flanders, J. Waxman, V.K. Shukla, P. Laidler, K. Horgan, L.E. Hughes, M.E. Elms, K.W. Schmid, B. Jasani, D.M. Quick, H.M. Wallace, D.J. De Friend, J. Bell, D. Wilkes, E. Anderson, C. West, A. Howell, B.C. Baguley, G.L. Cole, L.-M. Ching, W.P. Joseph, L.L. Thomsen, W.R. Wilson, L. Zhuang, L.J. Zwi

Title

Cell Cycle Control and Cancer Research Meeting Report

Conclusion

The meeting presented various studies on cell cycle control, oncogenes, and their implications in cancer research.

Automatic System for Acid-Base Titrations

University of the Balearic Islands 1990 n=13 publication Evidence: high

A. Cladera, A. Caro, J. M. Estela, V. Cerd/t

Title

Automatic System for Acid-Base Titrations

Hypothesis

The study aims to develop a fully automatic system for acid-base titrations using electrogeneration of ions.

Conclusion

The developed system allows for fully automated acid-base titrations with high sensitivity and low maintenance costs.

A Review of Severe Candida Infection in ICU Patients

St James' Hospital, Dublin, Ireland 2024 publication Evidence: moderate

Elnè Noppè, Julian Robert Paul Eloff, Sean Keane, Ignacio Martin-Loeches

Title

A Review of Severe Candida Infection in ICU Patients

Hypothesis

What are the risk factors, diagnosis, and treatment challenges of invasive candidiasis in ICU patients?

Conclusion

Invasive candidiasis remains a significant challenge in ICUs due to rising incidence and mortality rates, complicated by changing fungal ecology and resistance.

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