PubSort

Pubsort is a free search engine for publications that pre-summarizes each paper’s key findings, hypothesis, conclusion, and supporting evidence.

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Recent Publications

Breast Cancer Cells and Metastatic Behavior

Université Paris 13, CNRS FRE CSPBAT, Laboratoire de Chimie Structurale Biomoléculaire, UFR SMBH, Bobigny, France 2011 n=14 publication 10 minutes Evidence: high

Abdelkarim Mohamed, Vintonenko Nadejda, Starzec Anna, Robles Aniela, Aubert Julie, Martin Marie-Laure, Mourah Samia, Podgorniak Marie-Pierre, Rodrigues-Ferreira Sylvie, Nahmias Clara, Couraud Pierre-Olivier, Doliger Christelle, Sainte-Catherine Odile, Peyri Nicole, Chen Lei, Mariau Jérémie, Etienne Monique, Perret Gerard-Yves, Crepin Michel, Poyet Jean-Luc, Khatib Abdel-Majid, Di Benedetto Mélanie

Title

Breast Cancer Cells and Metastatic Behavior

Hypothesis

The extracellular matrix environment influences the metastatic potential of breast cancer cells.

Conclusion

The study shows that the extracellular matrix is sufficient to select for tumor cells with a stable metastatic phenotype.

Cost-Effectiveness of Diagnostic Options for Pneumocystis Pneumonia

Centers for Disease Control and Prevention 2011 n=33 publication Evidence: high

Julie R. Harris, Barbara J. Marston, Nalinee Sangrujee, Desiree DuPlessis, Benjamin Park

Title

Cost-Effectiveness of Diagnostic Options for Pneumocystis Pneumonia

Hypothesis

Cost-effectiveness comparisons of various diagnostic options for Pneumocystis pneumonia have not been presented.

Conclusion

PCR technologies combined with less-invasive specimen collection methods are more cost-effective for diagnosing Pneumocystis pneumonia than more invasive methods.

The IBEX Imaging Knowledge-Base: A Community Resource for Immunofluorescence Imaging

National Institute of Allergy and Infectious Diseases, National Institutes of Health 2024 publication 10 minutes Evidence: moderate

Yaniv Ziv, Anidi Ifeanyichukwu U., Arakkal Leanne, Arroyo-Mejías Armando J., Beuschel Rebecca T., Börner Katy, Chu Colin J., Clark Beatrice, Clatworthy Menna R., Colautti Jake, Coscia Fabian, Croteau Joshua, Denha Saven, Dever Rose, Dutra Walderez O., Fritzsche Sonja, Fullam Spencer, Gerner Michael Y., Gola Anita, Gollob Kenneth J., Hernandez Jonathan M., Hor Jyh Liang, Ichise Hiroshi, Jing Zhixin, Jonigk Danny, Kandov Evelyn, Kastenmüller Wolfgang, Koenig Joshua F.E., Kothurkar Aanandita, Kortekaas Rosa K., Kreins Alexandra Y., Lamborn Ian T., Lin Yuri, Morais Katia Luciano Pereira, Lunich Aleksandra, Luz Jean C.S., MacDonald Ryan B., Makranz Chen, Maltez Vivien I., McDonough John E., Moriarty Ryan V., Ocampo-Godinez Juan M., Olyntho Vitoria M., Oxenius Annette, Padhan Kartika, Remmert Kirsten, Richoz Nathan, Schrom Edward C., Shang Wanjing, Shi Lihong, Shih Rochelle M., Speranza Emily, Stierli Salome, Teichmann Sarah A., Veres Tibor Z., Vierhout Megan, Wachter Brianna T., Williams Margaret, Zangger Nathan, Germain Ronald N., Radtke Andrea J.

Title

The IBEX Imaging Knowledge-Base: A Community Resource for Immunofluorescence Imaging

Hypothesis

How can a centralized knowledge base improve the adoption and development of immunofluorescence imaging methods?

Conclusion

The IBEX Knowledge-Base facilitates open science and accelerates scientific discovery by providing a community-driven resource for sharing protocols, data, and validation results.

Mutation in AP1S1 Causes MEDNIK Syndrome

McGill University, Montréal, Québec, Canada 2008 n=17 publication 10 minutes Evidence: high

Montpetit Alexandre, Côté Stéphanie, Brustein Edna, Drouin Christian A., Lapointe Line, Boudreau Michèle, Meloche Caroline, Drouin Régen, Hudson Thomas J., Drapeau Pierre, Cossette Patrick

Title

Mutation in AP1S1 Causes MEDNIK Syndrome

Hypothesis

A mutation in the AP1S1 gene may cause the MEDNIK syndrome.

Conclusion

The study confirms that a mutation in the AP1S1 gene is responsible for MEDNIK syndrome and highlights its critical role in skin and spinal cord development.

Global Gradients of Coral Exposure to Environmental Stresses and Implications for Local Management

Macquarie University 2011 n=4000 publication 10 minutes Evidence: moderate

Maina Joseph, McClanahan Tim R., Venus Valentijn, Ateweberhan Mebrahtu, Madin Joshua

Title

Global Gradients of Coral Exposure to Environmental Stresses and Implications for Local Management

Hypothesis

How do different environmental stressors affect coral reefs globally?

Conclusion

Coral reefs are highly exposed to radiation stress, but local management of chronic human impacts can reduce this exposure.

The Genomic Analysis of Lactic Acidosis and Acidosis Response in Human Cancers

Duke University 2008 publication 10 minutes Evidence: high

Chen Julia Ling-Yu, Lucas Joseph E., Schroeder Thies, Mori Seiichi, Wu Jianli, Nevins Joseph, Dewhirst Mark, West Mike, Chi Jen-Tsan

Title

The Genomic Analysis of Lactic Acidosis and Acidosis Response in Human Cancers

Hypothesis

How do cells respond to lactic acidosis and how does that response relate to cancer phenotypes?

Conclusion

The study identifies a strong lactic acidosis response signature that correlates with better survival outcomes in breast cancer patients.

Bacterial Delivery of RNAi for Cancer Treatment

Institute of Pathology, Charité Campus Mitte 2010 publication Evidence: moderate

Hermann Krühn, Andrea Lage

Title

Bacterial Delivery of RNAi for Cancer Treatment

Hypothesis

Can transkingdom RNAi (tkRNAi) effectively deliver therapeutic shRNA to reverse multidrug resistance in cancer cells?

Conclusion

The study demonstrates that tkRNAi can successfully modulate the expression of the ABCB1 gene in cancer cells, reversing their drug-resistant phenotype.

The IBEX Imaging Knowledge-Base: A Community Resource for Immunofluorescence Imaging

Cornell University 2024 publication

Yaniv Ziv, Anidi Ifeanyichukwu U., Arakkal Leanne, Arroyo-Mejías Armando J., Beuschel Rebecca T., Börner Katy, Chu Colin J., Clark Beatrice, Clatworthy Menna R., Colautti Jake, Coscia Fabian, Croteau Joshua, Denha Saven, Dever Rose, Dutra Walderez O., Fritzsche Sonja, Fullam Spencer, Gerner Michael Y., Gola Anita, Gollob Kenneth J., Hernandez Jonathan M., Hor Jyh Liang, Ichise Hiroshi, Jing Zhixin, Jonigk Danny, Kandov Evelyn, Kastenmüller Wolfgang, Koenig Joshua F. E., Kothurkar Aanandita, Kortekaas Rosa K., Kreins Alexandra Y., Lamborn Ian T., Lin Yuri, Morais Katia Luciano Pereira, Lunich Aleksandra, Luz Jean C. S., MacDonald Ryan B., Makranz Chen, Maltez Vivien I., McDonough John E., Moriarty Ryan V., Ocampo-Godinez Juan M., Olyntho Vitoria M., Oxenius Annette, Padhan Kartika, Remmert Kirsten, Richoz Nathan, Schrom Edward C., Shang Wanjing, Shi Lihong, Shih Rochelle M., Speranza Emily, Stierli Salome, Teichmann Sarah A., Veres Tibor Z., Vierhout Megan, Wachter Brianna T., Williams Margaret, Zangger Nathan, Germain Ronald N., Radtke Andrea J.

Title

The IBEX Imaging Knowledge-Base: A Community Resource for Immunofluorescence Imaging

Conclusion

The IBEX Knowledge-Base enhances the adoption and development of immunofluorescence imaging methods by providing a centralized resource for researchers.

Predicting Cancer Treatment Response with Metagenes

Center for Biological Sequence Analysis, Technical University of Denmark 2011 n=1037 publication 10 minutes Evidence: high

Li Qiyuan, Eklund Aron C, Birkbak Nicolai J, Desmedt Christine, Haibe-Kains Benjamin, Sotiriou Christos, Symmans W Fraser, Pusztai Lajos, Brunak Søren, Richardson Andrea L, Szallasi Zoltan

Title

Predicting Cancer Treatment Response with Metagenes

Hypothesis

Can consistent metagenes derived from cancer expression profiles predict chemotherapy response?

Conclusion

The study found that metagenes derived from multiple data sets can effectively predict chemotherapy response in breast cancer and other tumor types.

How ERK1 and ERK2 Differ in Their Function and Movement in Cells

Institute of Neuroscience CNR, Pisa, Italy 2008 publication Evidence: high

Marchi Matilde, D'Antoni Angela, Formentini Ivan, Parra Riccardo, Brambilla Riccardo, Ratto Gian Michele, Costa Mario

Title

How ERK1 and ERK2 Differ in Their Function and Movement in Cells

Hypothesis

The different functions of ERK1 and ERK2 might depend on the properties of their cytoplasmic-nuclear trafficking.

Conclusion

ERK1 shuttles between the nucleus and cytoplasm at a much slower rate than ERK2, which affects its ability to transmit signals.

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