The IBEX Imaging Knowledge-Base: A Community Resource Enabling Adoption and Development of Immunofluoresence Imaging Methods
2024

The IBEX Imaging Knowledge-Base: A Community Resource for Immunofluorescence Imaging

publication 10 minutes Evidence: moderate

Author Information

Author(s): Yaniv Ziv, Anidi Ifeanyichukwu U., Arakkal Leanne, Arroyo-Mejías Armando J., Beuschel Rebecca T., Börner Katy, Chu Colin J., Clark Beatrice, Clatworthy Menna R., Colautti Jake, Coscia Fabian, Croteau Joshua, Denha Saven, Dever Rose, Dutra Walderez O., Fritzsche Sonja, Fullam Spencer, Gerner Michael Y., Gola Anita, Gollob Kenneth J., Hernandez Jonathan M., Hor Jyh Liang, Ichise Hiroshi, Jing Zhixin, Jonigk Danny, Kandov Evelyn, Kastenmüller Wolfgang, Koenig Joshua F.E., Kothurkar Aanandita, Kortekaas Rosa K., Kreins Alexandra Y., Lamborn Ian T., Lin Yuri, Morais Katia Luciano Pereira, Lunich Aleksandra, Luz Jean C.S., MacDonald Ryan B., Makranz Chen, Maltez Vivien I., McDonough John E., Moriarty Ryan V., Ocampo-Godinez Juan M., Olyntho Vitoria M., Oxenius Annette, Padhan Kartika, Remmert Kirsten, Richoz Nathan, Schrom Edward C., Shang Wanjing, Shi Lihong, Shih Rochelle M., Speranza Emily, Stierli Salome, Teichmann Sarah A., Veres Tibor Z., Vierhout Megan, Wachter Brianna T., Williams Margaret, Zangger Nathan, Germain Ronald N., Radtke Andrea J.

Primary Institution: National Institute of Allergy and Infectious Diseases, National Institutes of Health

Hypothesis

How can a centralized knowledge base improve the adoption and development of immunofluorescence imaging methods?

Conclusion

The IBEX Knowledge-Base facilitates open science and accelerates scientific discovery by providing a community-driven resource for sharing protocols, data, and validation results.

Supporting Evidence

  • The Knowledge-Base includes validation data for both recommended and non-recommended reagents.
  • It provides a venue for sharing protocols, videos, datasets, software, and publications.
  • A dedicated discussion forum fosters community engagement among researchers.

Takeaway

The IBEX Knowledge-Base is like a big library where scientists can share and find helpful information about special imaging techniques, making it easier for everyone to do their research.

Methodology

The Knowledge-Base was designed as a central hub for sharing information related to immunofluorescence imaging, including protocols, datasets, and validation results.

Potential Biases

Potential bias may arise from contributors selectively reporting only successful results.

Limitations

The Knowledge-Base relies on community contributions, which may vary in quality and completeness.

Digital Object Identifier (DOI)

10.5281/zenodo.7693278

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