Association of Positive Airway Pressure Adherence with Clinical Outcomes in Patients with Type 2 Diabetes and Obstructive Sleep Apnea
2024

Impact of PAP Adherence on Diabetes Outcomes in Patients with Sleep Apnea

Sample size: 355 publication 10 minutes Evidence: moderate

Author Information

Author(s): Bouloukaki Izolde, Stathakis George, Moniaki Violeta, Mavroudi Eleni, Tsiligianni Ioanna, Schiza Sophia

Primary Institution: University of Crete

Hypothesis

Is there an association between positive airway pressure (PAP) adherence and diabetes-related outcomes in patients with type 2 diabetes and obstructive sleep apnea?

Conclusion

Optimal PAP adherence in patients with type 2 diabetes and obstructive sleep apnea is linked to improved diabetes-related outcomes.

Supporting Evidence

  • Patients with optimal PAP adherence had a greater decrease in HbA1c levels compared to non-adherent patients.
  • Significant reductions in systolic and diastolic blood pressure were observed in the PAP adherent group.
  • Daytime sleepiness improved significantly in patients adhering to PAP therapy.

Takeaway

Using a special breathing machine called PAP helps people with diabetes and sleep apnea feel better and manage their blood sugar levels.

Methodology

This was a prospective study that included patients with type 2 diabetes and obstructive sleep apnea, assessing their PAP adherence and various health outcomes over an 8-year period.

Potential Biases

Potential bias due to self-reported adherence and the impact of the COVID-19 pandemic on follow-up.

Limitations

The study may have residual confounding due to unmeasured variables and was conducted at a single center, which may limit generalizability.

Participant Demographics

The majority of participants were married, had a higher level of education, and included both genders with a mean age of 62 years.

Statistical Information

P-Value

0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/diagnostics14242781

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