Exercise and quality of life in patients with cystic fibrosis: A 12-week intervention study
2011

Exercise and Quality of Life in Cystic Fibrosis Patients

Sample size: 42 publication 10 minutes Evidence: moderate

Author Information

Author(s): Schmidt Anne Mette BS, PT, Jacobsen Ulla PT, Bregnballe Vibeke RN, MHH, Olesen Hanne Vebert MD, PhD, Ingemann-Hansen Thorsten MD, PhD, Thastum Mikael PhD, Schietz Peter Oluf MD

Primary Institution: Aarhus University Hospital

Hypothesis

Increased exercise capacity is related to improved quality of life in patients with cystic fibrosis.

Conclusion

The study found that while exercise improved VO2max, it did not significantly enhance overall quality of life scores.

Supporting Evidence

  • Patients completing the exercise program showed a significant increase in VO2max.
  • Improvements were noted in the domains of treatment burden and emotional functioning.
  • No significant changes were observed in overall quality of life scores.

Takeaway

This study looked at how exercise affects people with cystic fibrosis. It showed that while exercise can make them stronger, it didn't really make them feel better overall.

Methodology

A 12-week unsupervised aerobic exercise program was conducted with 42 cystic fibrosis patients, measuring quality of life and exercise capacity before and after the intervention.

Potential Biases

Potential bias due to self-reported measures and the lack of a control group.

Limitations

The study had a high dropout rate and a short duration, which may limit the generalizability of the findings.

Participant Demographics

Patients aged 14 to 50 years, with a gender distribution of 15 males and 9 females.

Statistical Information

P-Value

0.014

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3109/09593985.2010.545102

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