Fix Your Eyes in the Space You Could Reach: Neurons in the Macaque Medial Parietal Cortex Prefer Gaze Positions in Peripersonal Space
2011

Macaque Medial Parietal Cortex Neurons and Gaze Positions

Sample size: 184 publication 10 minutes Evidence: high

Author Information

Author(s): Hadjidimitrakis Kostas, Breveglieri Rossella, Placenti Giacomo, Bosco Annalisa, Sabatini Silvio P., Fattori Patrizia

Primary Institution: Department of Human and General Physiology, University of Bologna, Bologna, Italy

Hypothesis

Cells in V6A would show stronger responses for targets presented in the reachable space.

Conclusion

Neurons in the medial PPC area V6A are more activated by gaze positions in the near, peripersonal space.

Supporting Evidence

  • A significant proportion of neurons were modulated by both gaze direction and depth.
  • The population activity of these neurons displayed a strong preference for peripersonal space.
  • 77% of cells had a statistically significant amount of modulation in the perisaccadic epoch.
  • 60-75% of V6A neurons preferred the near, peripersonal space.
  • 15-35% of V6A neurons exhibited excitation during eye movements in the extrapersonal space.

Takeaway

The study found that certain brain cells in monkeys are more active when they look at things that are close enough to reach.

Methodology

Single neuron recordings were performed in behaving macaques while they fixated on targets in 3D space.

Potential Biases

Potential bias in the selection of neuron types and the specific experimental setup may affect generalizability.

Limitations

The study was limited to a specific range of fixation distances and did not explore all potential variables affecting neuron activity.

Participant Demographics

Two male Macaca fascicularis monkeys were studied.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0023335

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