Genetic Variants Affecting Piglet Births and Leg Bumps in Pigs
Author Information
Author(s): Bakoev Siroj, Getmantseva Lyubov, Kolosova Maria, Bakoev Faridun, Kolosov Anatoly, Romanets Elena, Shevtsova Varvara, Romanets Timofey, Kolosov Yury, Usatov Alexander, Chu Mingxing
Primary Institution: Biotechnological Faculty, Don State Agrarian University, Russia
Hypothesis
SNPs identified from GWAS and selection signatures can be considered as significant variants controlling reproductive processes associated with the total number born.
Conclusion
The study identified significant SNPs involved in key physiological processes during sow pregnancy and linked to the risk of leg bumps in pigs.
Supporting Evidence
- 47 SNPs were identified that play a significant role during sow pregnancy.
- Some genes are associated with disorders of the nervous system and brain development.
- Six SNPs are associated with the formation of bumps on the legs of pigs.
- Targeted selection for reproductive efficiency may lead to changes in metabolic processes.
Takeaway
Scientists studied pigs to find genes that help determine how many piglets are born and found some genes that might also cause bumps on their legs.
Methodology
The study used genome-wide association studies (GWAS) and selection signatures to identify genetic variants associated with the total number of piglets born.
Participant Demographics
The study involved Large White breed pigs from a commercial breeding company in Russia.
Statistical Information
P-Value
0.00000011
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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