Reciprocality of Cognitive Impairment, Pain, and Depression: Modeling Within-Person Effects
2024

Cognitive Impairment, Pain, and Depression in Older Adults

Sample size: 11582 publication Evidence: moderate

Author Information

Author(s): Nakanishi Miharu, Perry Marieke, Bejjani Rachele, Yamaguchi Satoshi, Usami Satoshi, van der Steen Jenny

Primary Institution: Leiden University Medical Center

Hypothesis

The study explores the reciprocal risk between cognitive impairment, pain, and depressive symptoms in older adults.

Conclusion

Pain reduction may help prevent depressive symptoms and improve the quality of life for older adults.

Supporting Evidence

  • Pain at 6 months was associated with subsequent depressive symptoms.
  • Pain, depressive symptoms, and cognitive impairment were linked to poor quality of life 6 months later.

Takeaway

Older people often feel pain, sadness, and confusion, and this study found that feeling pain can lead to feeling sad later on.

Methodology

The study used longitudinal data and analyzed self-reported measures from older adults over 6 and 12 months.

Participant Demographics

Home-dwelling older adults with or without cognitive impairment.

Statistical Information

P-Value

0.024

Statistical Significance

p=0.024

Digital Object Identifier (DOI)

10.1093/geroni/igae098.3348

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