The Use of a Mobile Laboratory Unit in Support of Patient Management and Epidemiological Surveillance during the 2005 Marburg Outbreak in Angola
2011

Mobile Laboratory Unit in Marburg Outbreak Response

Sample size: 388 publication 10 minutes Evidence: high

Author Information

Author(s): Grolla Allen, Jones Steven M., Fernando Lisa, Strong James E., Ströher Ute, Möller Peggy, Paweska Janusz T., Burt Felicity, Pablo Palma Pedro, Sprecher Armand, Formenty Pierre, Roth Cathy, Feldmann Heinz

Primary Institution: Public Health Agency of Canada

Hypothesis

Can a mobile laboratory unit improve patient management and epidemiological surveillance during a Marburg virus outbreak?

Conclusion

The mobile laboratory unit was effective in providing rapid diagnostics and supporting outbreak response efforts.

Supporting Evidence

  • The mobile laboratory unit operated for 88 days and provided diagnostic results in less than 4 hours.
  • It tested 620 specimens, including oral swabs and blood samples.
  • There was a high concordance in test results between the mobile lab and the reference laboratory.

Takeaway

A special lab on wheels helped doctors quickly test for a dangerous virus during an outbreak, making it easier to help sick people.

Methodology

The mobile laboratory unit tested 620 specimens from 388 individuals using quantitative real-time PCR assays over 88 days.

Limitations

The study did not provide detailed epidemiological data and relied on specific sample types.

Participant Demographics

Most cases were found among females of child-bearing age and children under five years old.

Digital Object Identifier (DOI)

10.1371/journal.pntd.0001183

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