Dengue Disease Status in Chennai: A Retrospective Analysis (2006-2008)
Author Information
Author(s): Gunasekaran P., Kaveri K., Mohana S., Arunagiri Kavita, Babu B.V., Suresh Priya P., Padma Kiruba R., Kumar V., Senthil Sheriff A., Khaleefathullah
Primary Institution: King Institute of Preventive Medicine, Chennai, India
Hypothesis
Is there an overall increase in dengue prevalence over the three years period from 2006 to 2008?
Conclusion
The study indicates an increase in dengue IgM seropositivity, especially among pediatric cases, suggesting active dengue virus activity.
Supporting Evidence
- 686 out of 1593 screened cases were positive for IgM antibodies.
- 75.5% of the cases were pediatric.
- Statistically significant increase in IgM positivity was observed in 2008 compared to 2006.
- Secondary infections were noted in 16.47% of positive cases.
- Positivity was significantly high in the 1-5 and 6-12 year age groups.
Takeaway
The study looked at blood samples from people who might have dengue and found that many kids were getting sick, especially during the rainy season.
Methodology
Serum samples from suspected dengue cases were tested using MAC ELISA and IgG ELISA.
Limitations
The study is limited to retrospective data and may not capture all cases of dengue.
Participant Demographics
Of the 1593 cases, 968 were male and 625 were female, with 75.5% being pediatric cases.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
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