A sub-cubic time algorithm for computing the quartet distance between two general trees
2011

A Fast Algorithm for Computing Quartet Distance Between Trees

publication Evidence: high

Author Information

Author(s): Jesper Nielsen, Anders K. Kristensen, Thomas Mailund, Christian N. S. Pedersen

Primary Institution: Bioinformatics Research Centre (BiRC), Aarhus University

Hypothesis

Can we develop a faster algorithm for computing the quartet distance between general trees?

Conclusion

The new algorithm is significantly faster than previous methods for computing quartet distance.

Supporting Evidence

  • The algorithm runs in close to quadratic time in practice.
  • It is the fastest algorithm for computing quartet distance independent of the degree of inner nodes.
  • The implementation was tested on trees with up to 15,000 leaves.

Takeaway

The researchers created a new way to measure how different two trees are, and it's much quicker than older methods.

Methodology

The algorithm computes the quartet distance using a sub-cubic time complexity approach.

Limitations

The performance may vary depending on the topology of the trees being compared.

Digital Object Identifier (DOI)

10.1186/1748-7188-6-15

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