Post-Intubation Hypotension and Its Impact on Hospital Mortality
Author Information
Author(s): Heffner A, Swords D, Kline J, Jones A
Primary Institution: Carolinas Medical Center, Charlotte, NC, USA
Hypothesis
What is the incidence of post-intubation hypotension following emergency intubation and its association with in-hospital mortality?
Conclusion
Post-intubation hypotension occurs in nearly one-quarter of normotensive patients undergoing emergency intubation and is linked to higher in-hospital mortality.
Supporting Evidence
- PIH occurred in 76 out of 336 patients, which is 23%.
- The median time to first PIH was 11 minutes.
- Intubation for acute respiratory failure was the only independent predictor of PIH.
- Patients with PIH had a higher in-hospital mortality rate of 33% compared to 21% for those without PIH.
- Patients with PIH had longer mean ICU and hospital lengths of stay.
Takeaway
When doctors put a tube in your throat to help you breathe, some people might have low blood pressure afterward, which can make them sicker.
Methodology
A retrospective cohort study analyzing endotracheal intubations in a large urban emergency department over one year.
Participant Demographics
Median age of participants was 49 years, with 59% presenting with nontraumatic illness.
Statistical Information
P-Value
<0.01
Confidence Interval
95% CI = 1.1 to 4.0
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
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