MethCancerDB – aberrant DNA methylation in human cancer
2008

MethCancerDB: A Database for DNA Methylation in Cancer

Sample size: 4720 publication Evidence: moderate

Author Information

Author(s): Lauss M, Visne I, Weinhaeusel A, Vierlinger K, Noehammer C, Kriegner A

Primary Institution: Austrian Research Centers GmbH – ARC

Hypothesis

MethCancerDB aims to collect and annotate genes and sequences from published methylation studies to aid in cancer research.

Conclusion

MethCancerDB provides a comprehensive resource for researchers to access and analyze DNA methylation data related to cancer.

Supporting Evidence

  • MethCancerDB collects data from 348 sources.
  • The database allows researchers to filter and download gene and methylation information.
  • Entries are based on entire studies rather than individual observations.

Takeaway

MethCancerDB is like a big library that helps scientists find information about how DNA changes in cancer, making it easier to study and understand.

Methodology

The database was created by collecting and annotating 4720 entries from various studies, focusing on gene-centered data related to DNA methylation.

Limitations

The initial release of the database is based on existing studies and may not cover all relevant data.

Digital Object Identifier (DOI)

10.1038/sj.bjc.6604219

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