Exposures to Airborne Particulate Matter and Adverse Perinatal Outcomes: A Biologically Plausible Mechanistic Framework for Exploring Potential Effect Modification by Nutrition
2006

Air Pollution and Pregnancy Outcomes

publication Evidence: moderate

Author Information

Author(s): Kannan Srimathi, Misra Dawn P, Dvonch J. Timothy, Krishnakumar Ambika

Primary Institution: University of Michigan

Hypothesis

How does exposure to airborne particulate matter affect perinatal outcomes, and can nutrition modify this effect?

Conclusion

Exposure to particulate matter is linked to adverse perinatal outcomes like low birth weight, and nutrition may influence this relationship.

Supporting Evidence

  • Low birth weight affects 20 million infants worldwide.
  • Maternal PM exposure is correlated with several adverse perinatal outcomes.
  • Nutrition can modify the effects of PM exposure on reproductive health.

Takeaway

Breathing in dirty air can make babies smaller when they are born, but eating healthy food might help protect against this.

Methodology

The study proposes a conceptual framework integrating maternal and infant nutrition, air pollution exposure assessment, and epidemiology.

Potential Biases

Potential confounding factors such as socioeconomic status and nutritional status may bias the results.

Limitations

The specific biologic mechanisms linking PM exposure to perinatal outcomes are not fully understood.

Digital Object Identifier (DOI)

10.1289/ehp.9081

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication