Ovarian endometriomas and IVF: a retrospective case-control study
2011

Impact of Ovarian Endometriomas on IVF Outcomes

Sample size: 428 publication 10 minutes Evidence: moderate

Author Information

Author(s): Bongioanni Francesca, Revelli Alberto, Gennarelli Gianluca, Guidetti Daniela, Delle Piane Luisa, Holte Jan

Primary Institution: LIVET Infertility and IVF Clinic, Torino, Italy

Hypothesis

Does ovarian endometriosis affect the success rates of IVF compared to tubal infertility?

Conclusion

Ovarian endometriosis does not negatively impact IVF outcomes compared to tubal factor infertility, and prior laparoscopic surgery for endometriomas does not improve IVF results.

Supporting Evidence

  • Women with ovarian endometriosis had a higher cancellation rate but similar pregnancy rates compared to those with tubal infertility.
  • Previous laparoscopic surgery for endometriomas did not improve IVF outcomes.
  • Women with endometriosis required higher doses of gonadotropins for IVF.

Takeaway

Women with ovarian endometriosis can still have babies through IVF just like women with other infertility issues, and surgery to remove endometriomas might not help.

Methodology

Retrospective analysis of 428 IVF cycles comparing women with ovarian endometriosis to those with tubal infertility.

Potential Biases

Potential biases due to retrospective nature and selection of participants.

Limitations

The study is retrospective and may have biases inherent to such designs.

Participant Demographics

Women undergoing their first IVF attempt, with 254 having ovarian endometriosis and 174 with tubal infertility.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1477-7827-9-81

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