Antioxidant Properties of Vitex doniana and Mucuna pruriens Leaves
Author Information
Author(s): K. N. Agbafor, N. Nwachukwu
Primary Institution: Ebonyi State University
Hypothesis
The phytochemical constituents and antioxidant properties of Vitex doniana and Mucuna pruriens leaves can be scientifically evaluated.
Conclusion
The identified phytochemicals in the leaves contribute to their antioxidant activity, which may explain their therapeutic uses.
Supporting Evidence
- Phytochemical screening revealed the presence of saponins, tannins, anthraquinones, terpenoids, and flavonoids in all extracts.
- The water extract of Vitex doniana showed the highest inhibition of DPPH radical.
- The extracts significantly decreased liver MDA levels and increased SOD and CAT levels compared to the control.
Takeaway
The leaves of two plants can help protect our bodies from damage caused by bad things called free radicals.
Methodology
The study involved phytochemical screening and measurement of antioxidant activity using DPPH radical scavenging and liver enzyme levels in CCl4-treated rats.
Limitations
The study was limited to specific extracts and may not represent the full range of effects of the plants.
Participant Demographics
Adult male albino rats weighing 102–120 g.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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