West Nile Virus Outbreak in Israel, 2000
Author Information
Author(s): Miriam Weinberger, Silvio D. Pitlik, Dan Gandacu, Ruth Lang, Faris Nassar, Debora Ben David, Ethan Rubinstein, Avi Izthaki, Joseph Mishal, Ruth Kitzes, Yardena Siegman-Igra, Michael Giladi, Neora Pick, Ella Mendelson, Hanna Bin, Tamar Shohat, Michal Y. Chowers
Primary Institution: Rabin Medical Center, Petach Tikva, Israel
Hypothesis
What were the epidemiologic aspects of the West Nile virus outbreak in Israel in 2000?
Conclusion
The 2000 West Nile virus outbreak in Israel resulted in 417 confirmed cases and 35 deaths, highlighting a significant public health concern.
Supporting Evidence
- 417 cases of West Nile fever were confirmed in Israel from August 1 to October 31, 2000.
- 326 patients (78%) were hospitalized, with a case-fatality rate of 8.4%.
- Central nervous system involvement occurred in 73% of hospitalized patients.
Takeaway
In 2000, many people in Israel got sick from a virus called West Nile, and some even died, especially older folks.
Methodology
Serologic studies were performed on blood and CSF samples, and data were collected from hospitals and health district offices.
Limitations
The study did not thoroughly evaluate cross-reactivity with other flaviviruses.
Participant Demographics
Patients ranged from 6 months to 95 years old, with a mean age of 54.5 years; 50.1% were female.
Statistical Information
P-Value
p<0.0001
Statistical Significance
p<0.001
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