Effects of High-Dose EPA/DHA on Children with ADHD
Author Information
Author(s): Sorgi Paul J, Hallowell Edward M, Hutchins Heather L, Sears Barry
Primary Institution: Hallowell Center
Hypothesis
Insufficient levels of omega-3 fatty acids or lack of sufficient reduction of the AA:EPA ratio may explain inconsistent findings in previous studies on ADHD.
Conclusion
High-dose EPA/DHA supplementation may improve behavior in children with ADHD.
Supporting Evidence
- Supplementation resulted in significant increases in EPA and DHA levels.
- The AA:EPA ratio decreased significantly from 20.78 to 5.95.
- Behavioral improvements were reported by a psychiatrist blind to dosage adjustments.
- Significant correlation between AA:EPA ratio reduction and severity of illness scores.
Takeaway
Giving kids with ADHD a special fish oil can help them behave better.
Methodology
An eight-week open-label pilot study with nine children aged 8-16 receiving high-dose EPA/DHA supplementation.
Potential Biases
Potential bias due to lack of blinding for dosage adjustments and participant compliance.
Limitations
No placebo group, dietary intake not monitored, and dosage adjustments based on AA:EPA ratio may confound results.
Participant Demographics
Nine children aged 8-16, predominantly boys (67%), all diagnosed with ADHD.
Statistical Information
P-Value
p<0.01
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website