Pulse Wave Velocity and Diabetic Retinopathy
Author Information
Author(s): Ogawa Osamu, Hiraoka Kiyoko, Watanabe Takahiro, Kinoshita Junichiro, Kawasumi Masahiko, Yoshii Hidenori, Kawamori Ryuzo
Primary Institution: Juntendo University School of Medicine
Hypothesis
To investigate the clinical differences between pulse wave velocity and augmentation index in diabetic retinopathy.
Conclusion
BaPWV is associated with diabetic retinopathy, but AI is not.
Supporting Evidence
- BaPWV was significantly higher in patients with diabetic retinopathy than in individuals without the disease.
- The association between baPWV and diabetic retinopathy remained statistically significant after adjustment.
- AI was higher in patients with diabetic retinopathy, but not statistically significant.
Takeaway
This study found that a specific measurement called pulse wave velocity is linked to eye problems in diabetes, while another measurement called augmentation index is not.
Methodology
The study measured both augmentation index and brachial-ankle pulse wave velocity in 201 patients with type 2 diabetes to examine their relationship with diabetic retinopathy.
Potential Biases
Potential bias due to the exclusion of patients with macroangiopathy.
Limitations
The study's cross-sectional design limits the ability to establish causation.
Participant Demographics
Japanese patients with type 2 diabetes.
Statistical Information
P-Value
p<0.001
Confidence Interval
1.07–1.37
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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