Neuropathic Component Characteristics in Chronic Secondary Musculoskeletal Pain After Postmenopausal Osteoporotic Fractures: A Pilot Cross-Sectional Study
2024

Neuropathic Pain in Women with Osteoporotic Fractures

Sample size: 50 publication Evidence: moderate

Author Information

Author(s): Marie-Eva Pickering, Serge Perrot, Christian Dualé, Véronique Morel, Nicolas Macian, Bruno Pereira

Primary Institution: CHU Gabriel Montpied, Clermont-Ferrand, France

Hypothesis

The study aims to identify the presence of neuropathic characteristics in patients suffering from pain localized on the site of a previous osteoporotic fracture.

Conclusion

The study found that a significant percentage of patients with osteoporotic fractures exhibit neuropathic pain characteristics, which impair their quality of life and sleep.

Supporting Evidence

  • 21% of patients with vertebral fractures reported neuropathic pain characteristics.
  • 28% of patients with nonvertebral fractures reported neuropathic pain characteristics.
  • Patients with neuropathic pain had more intense pain and impaired sleep compared to those without.

Takeaway

Some women with broken bones from osteoporosis have a type of pain that feels different and can make it hard to sleep. Doctors need to pay more attention to this.

Methodology

This pilot cross-sectional study evaluated pain, neuropathic characteristics, and quality of life in patients with a history of osteoporotic fractures using various questionnaires.

Potential Biases

Potential bias may arise from the lack of prior assessment for neuropathic pain in patients.

Limitations

The study's sample size was small, which may limit the generalizability of the findings.

Participant Demographics

The participants were 50 postmenopausal women with a mean age of 69.1 years.

Statistical Information

P-Value

0.019

Confidence Interval

[0.18; 1.44]

Statistical Significance

p=0.019

Digital Object Identifier (DOI)

10.1155/prm/9766698

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