Measles outbreak in a community with very low vaccine coverage, the Netherlands.
2001

Measles Outbreak in a Low Vaccine Coverage Community

Sample size: 582 publication Evidence: high

Author Information

Author(s): van den Hof S, Meffre C M, Conyn-van Spaendonck M A, Woonink F, de Melker H E, van Binnendijk R S

Primary Institution: National Institute of Public Health and the Environment

Hypothesis

The study investigates the impact of low vaccine coverage on the spread of measles in a community.

Conclusion

The study confirms that measles infection leads to severe disease and highlights the importance of vaccination in preventing outbreaks.

Supporting Evidence

  • The measles outbreak started in a school with only 7% vaccine coverage.
  • The overall attack rate was 37%, with 213 clinical cases among 255 pupils.
  • None of the vaccinated pupils showed clinical symptoms.
  • The complication rate among symptomatic pupils was 25%.
  • Clusters of unvaccinated individuals hinder measles elimination efforts.

Takeaway

In a community where very few people got vaccinated, a measles outbreak happened, showing that vaccines are really important to keep everyone safe.

Methodology

The study involved tracking measles cases among pupils and household members during an outbreak.

Limitations

The study may not account for all factors influencing vaccine coverage and outbreak dynamics.

Participant Demographics

Participants included pupils from an elementary school and their household members.

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