Concentrated oat β-glucan, a fermentable fiber, lowers serum cholesterol in hypercholesterolemic adults in a randomized controlled trial
2007

Oat Fiber Lowers Cholesterol in Adults

Sample size: 75 publication Evidence: moderate

Author Information

Author(s): Katie M Queenan, Maria L Stewart, Kristen N Smith, William Thomas, R Gary Fulcher, Joanne L Slavin

Primary Institution: University of Minnesota

Hypothesis

Does concentrated oat β-glucan lower serum cholesterol levels in hypercholesterolemic adults?

Conclusion

Six grams of concentrated oat β-glucan per day for six weeks significantly reduced total and LDL cholesterol in subjects with elevated cholesterol.

Supporting Evidence

  • Oat β-glucan significantly reduced total cholesterol by 0.3 mmol/L.
  • LDL cholesterol decreased by 0.3 mmol/L in the treatment group.
  • The reduction in LDL cholesterol was significantly greater than in the control group.

Takeaway

Eating a special oat fiber can help lower bad cholesterol in people with high cholesterol levels.

Methodology

75 hypercholesterolemic adults were given either 6 grams of concentrated oat β-glucan or a control for six weeks, with blood samples taken to measure cholesterol levels.

Potential Biases

Potential bias in self-reported dietary intake and the exclusion of certain health conditions.

Limitations

The study had a relatively short duration of six weeks and a specific population of hypercholesterolemic adults.

Participant Demographics

Healthy, non-smoking men and women aged 22 to 65 with high cholesterol.

Statistical Information

P-Value

0.03

Statistical Significance

p = 0.03

Digital Object Identifier (DOI)

10.1186/1475-2891-6-6

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