DNA Methylation Patterns in Selaginella moellendorffii
Author Information
Author(s): Chan Agnes P, Melake-Berhan Admasu, O'Brien Kimberly, Buckley Stephanie, Quan Hui, Chen Dan, Lewis Matthew, Banks Jo Ann, Rabinowicz Pablo D
Primary Institution: J. Craig Venter Institute (JCVI)
Hypothesis
What are the DNA methylation patterns in the genome of the early divergent vascular plant Selaginella moellendorffii?
Conclusion
The study reveals that genes and repeats are differentially methylated in the genome of Selaginella moellendorffii.
Supporting Evidence
- The study provides the first glimpse into the epigenetic landscape of Selaginella moellendorffii.
- Methylation filtration genomic libraries were used to select unmethylated DNA clones.
- Chloroplast DNA was enriched in the filtered library, indicating DNA methylation in the S. moellendorffii genome.
- The highest-copy repeats were largely under-represented in the methylation filtered library.
Takeaway
This study looks at how DNA is marked in a plant called Selaginella moellendorffii, showing that some parts of its DNA are marked differently than others.
Methodology
The study used methylation filtration techniques to analyze DNA methylation patterns in Selaginella moellendorffii.
Digital Object Identifier (DOI)
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