Airway sizes and proportions in children quantified by a video-bronchoscopic technique
2006

Measuring Airway Sizes in Children

Sample size: 125 publication Evidence: moderate

Author Information

Author(s): Ian B Masters, Robert S Ware, Paul V Zimmerman, Brian Lovell, Richard Wootton, Paul V Francis, Anne B Chang

Primary Institution: University of Queensland

Hypothesis

The large airways undergo proportionate growth when compared to the cricoid as a reference point and that gender and the usual childhood anthropometric factors influence airway size.

Conclusion

The large airways progressively increase in cross-sectional area size, maintain constant proportional relationships to the cricoid, and are gender independent across childhood.

Supporting Evidence

  • Airway size increased with age but proportions remained constant.
  • The LMS was 21% smaller than the RMS.
  • No significant gender differences in airway size were found.

Takeaway

This study looked at how big children's airways are and found that they grow as kids get older, but their sizes compared to a specific part of the throat stay the same.

Methodology

A validated videobronchoscope technique was used to measure in-vivo airway cross-sectional areas of 125 children, with various statistical analyses performed to assess relationships.

Potential Biases

Potential bias in patient selection as only symptomatic children were included.

Limitations

The study used symptomatic patients as 'normals' and did not analyze for other potential confounders such as drug exposure in pregnancy.

Participant Demographics

125 children aged 10 years or younger, with 87 males and 38 females.

Statistical Information

P-Value

0.0001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2466-6-5

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