Dog as an outgroup to human and mouse
2007

Dog as an Outgroup to Human and Mouse

publication Evidence: high

Author Information

Author(s): Gerton Lunter

Primary Institution: University of Oxford

Hypothesis

Is the dog an outgroup to the primate–rodent clade?

Conclusion

The study provides new evidence supporting the consensus phylogeny that places the dog as an outgroup to both human and mouse.

Supporting Evidence

  • The results show clear support for the rodent–primate grouping.
  • Numerous recent studies consistently support the dog as an outgroup to human and mouse.
  • TE-based studies are not expected to suffer from long branch attraction.

Takeaway

This study shows that dogs are more closely related to humans and mice than previously thought, and that the way we analyze their relationships can lead to mistakes.

Methodology

The study used a novel summary statistic based on the distribution of transposable elements in pairwise alignments to analyze phylogenetic relationships.

Potential Biases

Potential bias from long branch attraction in molecular phylogenetic inference.

Limitations

The study's conclusions may be influenced by biases in phylogenetic analysis methods.

Digital Object Identifier (DOI)

10.1371/journal.pcbi.0030074

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