Reducing inappropriate antibiotic prescribing for acute uncomplicated bronchitis: a systemwide quality improvement project
2024

Reducing Inappropriate Antibiotic Prescribing for Bronchitis

Sample size: 8176 publication Evidence: high

Author Information

Author(s): Sabrina Williams, Julie Engels, Sara Ogrin, Nolan Rossman, Rosemary Olivero

Primary Institution: Michigan State University College of Human Medicine

Hypothesis

Did a bundle of antimicrobial stewardship interventions reduce inappropriate antibiotic prescriptions for acute uncomplicated bronchitis?

Conclusion

The study found a significant reduction in inappropriate antibiotic prescriptions for acute uncomplicated bronchitis after implementing stewardship interventions.

Supporting Evidence

  • The proportion of inappropriate prescriptions decreased from 44.9% to 32.5% after the interventions.
  • Statistically significant decreases in inappropriate prescriptions were observed in specific months.
  • The study included a large sample size of 8,176 encounters.

Takeaway

The study showed that by using specific strategies, doctors can prescribe fewer unnecessary antibiotics for bronchitis, which is important for keeping people healthy.

Methodology

A quasi-experimental quality improvement study comparing inappropriate antibiotic prescriptions before and after interventions over a 2-year period.

Potential Biases

Inappropriate prescribing was based on documentation accuracy in electronic medical records, which may not be complete.

Limitations

The study was retrospective and relied on provider-selected ICD-10 codes, which may introduce selection bias.

Participant Demographics

The study included adult patients with acute uncomplicated bronchitis, with no significant differences in demographics noted.

Statistical Information

P-Value

P < 0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1017/ash.2024.465

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