Blood-Brain Barrier Breakdown and Blood-Brain Communication in Neurological and Psychiatric Diseases
2011

Blood-Brain Barrier Breakdown and Communication in Brain Diseases

Editorial

Author Information

Author(s): Alon Friedman, Daniela Kaufer

Primary Institution: Ben-Gurion University of the Negev

Hypothesis

How does blood-brain barrier dysfunction contribute to various neurological diseases?

Conclusion

Blood-brain barrier dysfunction is linked to a range of neurological diseases and raises important questions about its role in symptoms and treatment.

Supporting Evidence

  • BBB dysfunction is associated with various neurological diseases like stroke and epilepsy.
  • Experimental evidence suggests that BBB dysfunction may lead to neuronal network degeneration.
  • New imaging techniques are being developed to assess BBB permeability in both animals and humans.
  • Research highlights the need for new methods to study BBB dysfunction ex vivo.

Takeaway

The blood-brain barrier is like a gate that protects the brain, but when it breaks, it can cause many brain problems.

Digital Object Identifier (DOI)

10.1155/2011/431470

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