Type 2 Diabetes in Children and Young People: Global Trends and Characteristics
Author Information
Author(s): Gesuita Rosaria, Eckert Alexander J., Besançon Stéphane, Crimmins Nancy A., Cavallo Fred, Kim Jaehyun, Jefferies Craig, Gevers Evelien F., Vamvakis Anastasios, Shah Sejal, Amed Shazhan, Cherubini Valentino
Primary Institution: Università Politecnica delle Marche, Ancona, Italy
Hypothesis
The study evaluates the frequency and clinical characteristics of young people presenting with type 2 diabetes from the SWEET Registry between 2012 and 2021.
Conclusion
The study found a significant increase in the proportion of type 2 diabetes diagnoses among young people globally, highlighting regional differences.
Supporting Evidence
- 4.8% of new diabetes cases were type 2 diabetes.
- The proportion of type 2 diabetes increased from 3.2% to 6.0% from 2012/2013 to 2020/2021.
- High variability in type 2 diabetes prevalence was observed across regions.
- The median HbA1c was highest in Asia/Middle East and Africa and lowest in Europe.
Takeaway
More kids and teens are getting type 2 diabetes now than before, and it varies a lot depending on where they live.
Methodology
This is a longitudinal observational study using data from the SWEET Registry, which collects demographic and clinical data on children and adolescents with diabetes.
Potential Biases
Potential biases may arise from incomplete data and the reliance on provider diagnosis for diabetes types.
Limitations
The study lacks information on ethnic minorities, social and cultural environments, and may have missing data due to changes in participating centers.
Participant Demographics
Participants included children and adolescents under 21 years old diagnosed with diabetes from various regions worldwide.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI 5.9, 12.3
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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