Evaluating Left Ventricular Diastolic Function with Cardiovascular Magnetic Resonance
Author Information
Author(s): Vikas K Rathi, Mark Doyle, June Yamrozik, Ronald B Williams, Ketheswaram Caruppannan, Craig Truman, Diane Vido, Robert W Biederman
Primary Institution: Allegheny General Hospital, Drexel University College of Medicine
Hypothesis
Assessment of diastolic function by examination of mitral valve and pulmonary vein flow conditions is clinically feasible using 3D CMR-PC imaging.
Conclusion
CMR can accurately assess diastolic function and provides reliable flow data comparable to TTE.
Supporting Evidence
- CMR successfully imaged blood flow in all cases (100%) while TTE only imaged 68% of cases.
- CMR and TTE measurements of mitral valve flow velocities correlated well (r = 0.81).
- Bland-Altman analysis showed excellent agreement for E:A ratio and deceleration time between CMR and TTE.
Takeaway
Doctors can use a special MRI to check how well the heart fills with blood, which helps them understand heart problems better.
Methodology
Left ventricular diastolic function was assessed in 31 subjects using CMR and compared with TTE evaluation.
Limitations
Diastolic flow indices are affected by pressure gradients, heart rate, and hydration status.
Participant Demographics
21 male and 10 female subjects with a mean age of 60 ± 14 years.
Statistical Information
P-Value
< 0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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