An epidemiological study of cancer in adult twins born in Norway 1905–1945
2001

Cancer Risk in Norwegian Twins

Sample size: 23334 publication Evidence: moderate

Author Information

Author(s): Iversen T, Tretli S, Kringlen E

Primary Institution: The Department of Oncology, Ullevaal Hospital, Oslo, Norway

Hypothesis

Twins born in Norway between 1905 and 1945 have a different risk of developing cancer compared to the general population.

Conclusion

Twins showed a reduced risk of malignant disease, particularly for skin melanomas and certain other cancers.

Supporting Evidence

  • Twins showed a standardized incidence rate of 0.90 for females and 0.95 for males.
  • A significant reduced incidence of malignant melanomas of the skin was observed.
  • The incidence of colorectal cancer tended to be reduced for both sexes.
  • In females, the incidence of tumours of the central nervous system and lungs were reduced.

Takeaway

This study looked at twins in Norway and found that they are less likely to get cancer than other people.

Methodology

The study linked data from twins to the Cancer Registry of Norway to analyze cancer incidence.

Limitations

The reasons for the reduced cancer incidence among twins are not explained.

Participant Demographics

Twins born in Norway between 1905 and 1945.

Statistical Information

Confidence Interval

95% CI 0.85–0.94 for females, 95% CI 0.90–0.99 for males

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1054/bjoc.2001.1827

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