SELF-REPORTED DISCRIMINATION AND BRAIN STRUCTURAL ABNORMALITIES: THE MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS
2024

Discrimination and Brain Health in Different Races

Sample size: 1430 publication Evidence: moderate

Author Information

Author(s): Forrester Sarah, Tanley Jordan, Bancks Michael, Luchsinger José, Rapp Stephen, Jiminez Marcia P, Bryan Robert, Hughes Timothy

Hypothesis

Does self-reported discrimination affect brain imaging findings associated with aging and Alzheimer's disease across different racial/ethnic groups?

Conclusion

Experiencing racial discrimination is linked to greater brain health issues, particularly in Black adults.

Supporting Evidence

  • Black and Hispanic adults are at greater risk for Alzheimer's disease compared to White adults.
  • Racial discrimination was positively associated with greater white matter hyperintensity volume.
  • Stronger associations between racial discrimination and brain health were found in Black participants.

Takeaway

If people face discrimination, it can hurt their brain health, especially for Black people.

Methodology

Data from the MESA study was used, involving brain imaging and regression models adjusted for various covariates.

Participant Demographics

6814 participants initially enrolled, including 38% White, 28% Black, 22% Hispanic, and 12% Chinese Americans.

Statistical Information

P-Value

0.008

Confidence Interval

2.24(1.07, 4.70)

Statistical Significance

p = 0.008

Digital Object Identifier (DOI)

10.1093/geroni/igae098.1309

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication