Methyl 2-[2-(2,6-dichloro-4-nitro­anilino)-3,5-dinitro­phen­yl]acetate
2011

Study of a New Compound Derived from Diclofenac

publication Evidence: moderate

Author Information

Author(s): Tariq Muhammad Ilyas, Jameel Muhammad, Tahir M. Nawaz, Ali Toqir, Rizwan Muhammad

Primary Institution: University of Sargodha, Sargodha, Pakistan

Hypothesis

The synthesized compound may exhibit enhanced properties compared to traditional NSAIDs.

Conclusion

The new compound shows a unique crystal structure with significant hydrogen bonding interactions.

Supporting Evidence

  • The compound is derived from diclofenac, a known NSAID.
  • It exhibits a unique crystal structure with specific dihedral angles.
  • The study highlights the potential of nitro-substituted NSAIDs in cancer treatment.

Takeaway

Scientists made a new chemical compound from a common painkiller and found it has interesting properties.

Methodology

The compound was synthesized by nitrating diclofenac and then crystallizing it from a solvent mixture.

Digital Object Identifier (DOI)

10.1107/S1600536811007720

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