Gut Microbiota Dysbiosis and Musculoskeletal Health in Older People
Author Information
Author(s): José Neto, Duarte Brito Mário, Gomes Cristiano dos Santos, Corrêa Luana Caroline de Assunção Cortez, Guerra Gerlane Coelho Bernardo, Guerra Ricardo Oliveira
Primary Institution: Federal University of Rio Grande do Norte, Natal, Brazil
Hypothesis
The study aims to explore the influence of gut microbiota dysbiosis on sarcopenia, osteoporosis, and osteosarcopenia in older adults.
Conclusion
The systematic review will compile evidence on how gut microbiota dysbiosis affects musculoskeletal function in older individuals.
Supporting Evidence
- Sarcopenia and osteoporosis are prevalent conditions in older adults that can lead to increased risk of fractures and disability.
- Dysbiosis of the gut microbiota may contribute to musculoskeletal disorders in aging.
- The review aims to identify gaps in current knowledge regarding gut microbiota and musculoskeletal health.
Takeaway
This study is looking at how the bacteria in our gut might affect our muscles and bones as we get older.
Methodology
The review will analyze observational studies and synthesize data on gut microbiota dysbiosis and its relationship with musculoskeletal health in older adults.
Potential Biases
Potential bias risks include variability in study quality and the possibility of high-risk studies affecting overall results.
Limitations
The limited number of studies linking osteosarcopenia with intestinal microbiota dysbiosis may constrain the overall conclusions of the review.
Participant Demographics
Older adults aged 65 and over.
Digital Object Identifier (DOI)
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