Epithelial ovarian cancer: a cytokine propelled disease?
1991
Cytokines and Ovarian Cancer
Editorial
Author Information
Author(s): S. Malik, F. Balkwill
Primary Institution: Biological Therapies Laboratory, Imperial Cancer Research Fund
Hypothesis
Cytokines may play a significant role in the pathogenesis and progression of ovarian cancer.
Conclusion
Cytokines produced by ovarian cancer cells may contribute to tumor progression and metastasis.
Supporting Evidence
- Cytokines can inhibit tumor growth and have been used in cancer therapy.
- Constitutive production of cytokines by ovarian cancer cells has been demonstrated.
- TNF has been shown to enhance tumor metastasis in experimental models.
Takeaway
Cytokines are tiny proteins that can help cancer grow, and this study looks at how they might be involved in ovarian cancer.
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