Living Review of Single-Cell and Spatial Omic Technologies
Author Information
Author(s): De Jonghe Joachim, Opzoomer James W., Vilas-Zornoza Amaia, Nilges Benedikt S., Crane Peter, Vicari Marco, Lee Hower, Lara-Astiaso David, Gross Torsten, Morf Jörg, Schneider Kim, Cudini Juliana, Ramos-Mucci Lorenzo, Mooijman Dylan, Tiklová Katarína, Salas Sergio Marco, Langseth Christoffer Mattsson, Kashikar Nachiket D., The scTrends Consortium, Carrami Eli M., McIntyre Rebecca, Swerner Casey Benjamin, Hessel Edith M., Kapourani ChantrioInt-Andreas, Regep Cristian, Roberts Charles E.S.
Conclusion
This review provides a comprehensive overview of current commercial single-cell and spatial omic technologies, highlighting their applications in drug discovery and biomedical research.
Supporting Evidence
- Single-cell genomic profiling technologies are becoming the standard for studying complex biological samples.
- The review highlights both mature and emerging commercial platforms in the field.
- Emerging methodologies may expand the scope for data generation in pharmaceutical research.
- Technologies discussed include microfluidics, plate-based methods, and spatial transcriptomics.
Takeaway
This study looks at new technologies that help scientists understand cells better, which can lead to new medicines and treatments.
Methodology
The review catalogs various commercial platforms and methodologies in single-cell and spatial omics, discussing their applications and trends.
Limitations
The review may not cover all emerging technologies due to the rapid pace of advancements in the field.
Digital Object Identifier (DOI)
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