ASSOCIATIONS OF SOCIAL RELATIONSHIPS WITH INFLAMMATORY, CARDIOVASCULAR AND IMMUNE CELL BIOMARKERS
2024
Social Relationships and Health Biomarkers
Sample size: 875
publication
Evidence: moderate
Author Information
Author(s): Ragab Ahmed, Chen Jiachen, Cao Yumeng, Doyle Margaret, Murabito Joanne, Lunetta Kathryn
Primary Institution: Boston University
Hypothesis
How do social relationships affect inflammatory, cardiovascular, and immune cell biomarkers?
Conclusion
Social isolation is linked to various inflammatory and cardiovascular biomarkers.
Supporting Evidence
- Social isolation is linked to higher risks of morbidity and mortality.
- SNI was positively associated with several inflammatory biomarkers.
- SNI was positively associated with various cardiovascular proteins.
- SNI was negatively associated with multiple cardiovascular biomarkers.
Takeaway
Having friends and being social can help keep your body healthy by reducing inflammation and heart problems.
Methodology
Linear Mixed Effects models were used to analyze the relationship between the Social Network Index and various biomarker datasets.
Limitations
The study did not include immune cell phenotypes in the full sample.
Participant Demographics
Framingham Heart Study Offspring participants with a mean age of 61.
Statistical Information
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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