Aneurysm Formation at the Internal Carotid Artery Bifurcation and Its Relation to Vascular Geometry
Author Information
Author(s): Akdağ Rifat, Soylu Ugur, Uçkun Özhan Merzuk, Polat Ömer, Gürpınar İdris, Dağlıoğlu Ergün
Primary Institution: Bursa Yüksek İhtisas Training and Research Hospital, University of Health Science
Hypothesis
The effect of ICA bifurcation geometry on aneurysm formation is similar to that of the morphological risk factors on other bifurcation regions.
Conclusion
Bifurcation geometry significantly impacts the likelihood of aneurysm formation, with the BifA angle being a better predictor than the α angle.
Supporting Evidence
- The study included 163 patients, with 58 having ICA bifurcation aneurysms.
- Significant predictors of aneurysm formation included the BifA angle and P1 diameter.
- The optimal BifA threshold for differentiating between aneurysmal and non-aneurysmal bifurcations was found to be 210°.
Takeaway
This study found that the shape of blood vessels at a certain point can affect the chances of having an aneurysm, which is like a balloon in a blood vessel.
Methodology
The study evaluated computerized tomography angiography data of 1512 patients, comparing those with and without ICA bifurcation aneurysms.
Potential Biases
Potential measurement bias due to manual data collection and the retrospective design.
Limitations
The study's retrospective nature and the inability to control for all genetic and environmental factors affecting aneurysm formation.
Participant Demographics
Average age of participants was 47.6 years, with 50.9% being female.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI 0.877–0.946
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website