The effects of Bleomycin A5 on infantile maxillofacial haemangioma
2011
Effects of Bleomycin A5 on Infantile Hemangiomas
Sample size: 82
publication
Evidence: high
Author Information
Author(s): Luo Quan-feng, Zhao Fu-yun
Primary Institution: Peking University School and Hospital of Stomatology
Hypothesis
To examine the effects of bleomycin A5 on infantile maxillofacial haemangiomas.
Conclusion
Infantile haemangioma could be effectively treated with bleomycin A5 without serious side effects.
Supporting Evidence
- All the haemangiomas involuted completely after treated with bleomycin A5.
- Smaller haemangiomas had better recovery of skin color and less scar formation.
- The treatment was effective without serious side effects.
Takeaway
Bleomycin A5 can help make baby tumors on the face go away without causing big problems.
Methodology
Bleomycin A5 was administered through multiple intralesional injections, with dosages adjusted based on patient age and lesion size.
Limitations
The study did not address the long-term effects of treatment or the potential for recurrence.
Participant Demographics
34 male and 48 female infants, mostly under 4 months old.
Digital Object Identifier (DOI)
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