Therapeutic Potential of a Natural Blend of Aronia melancarpa, Lonicera caerulea, and Echinacea purpurea Extracts in Treating Upper Respiratory Tract Infections: Preliminary Clinical and In Vitro Immunomodulatory Insights
2024

Natural Blend of Aronia, Lonicera, and Echinacea for Treating Respiratory Infections

Sample size: 61 publication 10 minutes Evidence: moderate

Author Information

Author(s): Katarzyna Zima, Marta Sochocka, Michał Ochnik, Barbara Khaidakov, Krzysztof Lemke, Paulina Kowalczyk

Primary Institution: Medical University of Gdańsk

Hypothesis

The ELA blend demonstrates efficacy in reducing the incidence, severity, and duration of upper respiratory tract infections (URTIs) in individuals susceptible to such infections.

Conclusion

The ELA blend significantly reduced the incidence of URTIs and throat-related symptoms, highlighting its potential as a treatment option.

Supporting Evidence

  • The ELA blend significantly reduced the incidence of URTIs during the observation period (2 vs. 8; p = 0.044).
  • Fewer patients in the ELA blend group reported throat-related symptoms compared to the placebo group (8 vs. 16; p = 0.038).
  • Baseline production of cytokines increased after ELA blend treatment, indicating immunomodulatory effects.

Takeaway

This study found that a mix of natural plant extracts can help people get fewer colds and feel better when they do get sick.

Methodology

A randomized, double-blind, placebo-controlled trial with 61 participants over a 60-day treatment and follow-up period.

Potential Biases

Potential biases were minimized through a double-blind design.

Limitations

The study had a relatively small sample size and a short observation period.

Participant Demographics

Participants aged 18–70 years, both men and women, with a median age of 59.

Statistical Information

P-Value

p = 0.044

Confidence Interval

−0.01 to 0.33

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/ijms252413436

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