Anticoagulation Complications in Hemodialysis Patients with Acute Kidney Injury in Ethiopia
Author Information
Author(s): Kedir Hanan Muzeyin, Yabeyu Abdella Birhan, Ejigu Addisu Melkie, Tadesse Tamrat Assefa, Sisay Eskinder Ayalew
Primary Institution: Addis Ababa University
Hypothesis
This study aimed to evaluate anticoagulation outcomes and related factors in hemodialysis patients with acute kidney injury at selected hospitals in Ethiopia.
Conclusion
Clotting affected 19.4% of participants, while bleeding occurred in 15.4%, highlighting the need for close monitoring.
Supporting Evidence
- Extracorporeal circuit clotting was detected in 34 patients during 39 dialysis sessions.
- Bleeding incidents occurred in 27 patients across 29 sessions.
- A statistically significant association was found between the total number of HD treatments and blood flow rate with incidents of clotting.
Takeaway
This study looked at patients on dialysis and found that some had problems with blood clots and bleeding, which means doctors need to watch them closely.
Methodology
A prospective, multicenter observational study was conducted, analyzing data from hemodialysis sessions and patient outcomes.
Potential Biases
Potential biases may arise from the observational nature of the study and the specific settings in which it was conducted.
Limitations
The study did not exclude patients with comorbidities that could impact anticoagulation outcomes.
Participant Demographics
The study included 175 patients, with a mean age of 40 years, and a nearly equal distribution of males (50.9%) and females (49.1%).
Statistical Information
P-Value
0.004
Confidence Interval
95% CI, 1.227–3.043
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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