Relevance of Anthocyanin Metabolites Generated During Digestion on Bioactivity Attributed to Intact Anthocyanins
2024

Anthocyanin Metabolites and Their Health Benefits

publication Evidence: moderate

Author Information

Author(s): Victoria-Campos Claudia I., Ornelas-Paz José de Jesús, Rios-Velasco Claudio, Ruiz-Cruz Saul, Ornelas-Paz Juan, Del Toro-Sánchez Carmen L., Márquez-Ríos Enrique, Calderón-Loera Rogelio

Primary Institution: Facultad de Enfermería y Nutrición, Universidad Autónoma de San Luis Potosí

Hypothesis

The review aims to analyze the contributions of anthocyanin metabolites generated during digestion to human health.

Conclusion

Anthocyanin metabolites significantly contribute to the biological actions attributed to intact anthocyanins, despite their low bioavailability.

Supporting Evidence

  • Anthocyanins have shown antioxidant, anticancer, antidiabetic, and anti-inflammatory effects.
  • Less than 5% of consumed anthocyanins are absorbed in intact form in the digestive tract.
  • Anthocyanins are highly susceptible to chemical modification due to medium pH.
  • Anthocyanin metabolites may exert protective effects on human health.
  • Few studies have accurately identified anthocyanin metabolites in biological samples.

Takeaway

Eating foods with anthocyanins, like berries, is good for you, but your body might change them into different forms that are also healthy.

Methodology

The review prioritizes studies using purified or semi-purified anthocyanins under digestion or physiological conditions.

Potential Biases

The reliance on plant extracts may compromise the accurate identification of anthocyanin metabolites.

Limitations

The review highlights the lack of studies using pure anthocyanins and the challenges in accurately identifying anthocyanin metabolites.

Digital Object Identifier (DOI)

10.3390/foods13244066

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