Post-COVID Mortality Risk in Brazil
Author Information
Author(s): Nádia Cristina Pinheiro Rodrigues, Mônica Kramer de Noronha Andrade
Primary Institution: Escola Nacional de Saúde Pública Sérgio Arouca/Fundação Oswaldo Cruz, Brazil
Hypothesis
What factors are associated with post-COVID mortality in severe acute respiratory syndrome cases in Brazil from 2020 to 2023?
Conclusion
Vaccination against COVID-19 showed a protective effect up to one year after symptoms, but after that, the risk of death increased for vaccinated individuals.
Supporting Evidence
- 5,157 deaths were recorded out of 15,147 reported SARS/COVID-19 cases.
- 91.5% of deaths occurred within the first year after symptoms.
- Vaccination reduced the risk of death by 8% in the medium term but increased it in the long term.
Takeaway
This study looked at people in Brazil who got really sick from COVID-19 and found that getting vaccinated helped at first, but later on, it seemed to make things worse for some people.
Methodology
Retrospective cohort study using notification data of SARS classified as COVID-19 from the Brazilian National Information System from 2020 to 2023.
Potential Biases
Potential selection bias due to focusing only on severe cases and incomplete data in some notification fields.
Limitations
The study only included severe cases of COVID-19, which may not reflect the overall mortality rates and could introduce selection bias.
Participant Demographics
Included individuals with severe acute respiratory syndrome, with a focus on older adults and those with comorbidities.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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