Effects of Lactobacillus plantarum on Dental Caries and Obesity
Author Information
Author(s): Yang Wei, Jiang Mingxin, Chen Bairu, Jiang Kongzhao, Ma Nan, Li Yimin, Wang Meng, Bao Meihua, Wang Chengyue, Yang Xiaopeng
Primary Institution: Affiliated Stomatology Hospital of Jinzhou Medical University
Hypothesis
Can Lactobacillus plantarum ATCC 14917 prevent dental caries and obesity in rat models?
Conclusion
Lactobacillus plantarum ATCC 14917 can reduce tooth decay and control weight gain.
Supporting Evidence
- Lactobacillus plantarum ATCC 14917 inhibited the growth of Streptococcus mutans.
- The demineralization rate of enamel decreased by 44.10%.
- Lactobacillus plantarum improved the balance of intestinal flora.
- The LP group showed reduced weight gain compared to the CA_OB group.
- Serum biochemical indices improved in the LP group.
Takeaway
This study shows that a type of good bacteria called Lactobacillus plantarum can help keep your teeth healthy and stop you from getting too heavy.
Methodology
The study involved in vitro tests for antibacterial properties and in vivo tests on rats fed a high-fat and high-sugar diet.
Potential Biases
Potential bias in the selection of animal models and dietary conditions.
Limitations
The study was conducted on rats, which may not fully represent human responses.
Participant Demographics
Male Sprague Dawley rats, 3 weeks old.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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