Sickle cell trait and priapism: a case report and review of the literature
2008
Sickle Cell Trait and Priapism: A Case Report
publication
Evidence: low
Author Information
Author(s): Brian F. Birnbaum, Joseph J. Pinzone
Primary Institution: The Ohio State University
Hypothesis
Is sickle cell trait a significant factor in the development of acute priapism?
Conclusion
Sickle cell trait may be an important predisposing factor for priapism, which should be included in discussions about the condition.
Supporting Evidence
- Sickle cell trait is typically benign but may lead to complications like priapism.
- Previous studies have indicated a potential link between sickle cell trait and priapism.
- Phosphodiesterase-5 inhibitors, commonly used for erectile dysfunction, may have a complex relationship with priapism in sickle cell trait.
Takeaway
A man with sickle cell trait had a painful erection that wouldn't go away, and doctors think his condition might have caused it.
Methodology
Case report and literature review.
Limitations
The study is based on a single case report and literature review, which may not represent broader trends.
Participant Demographics
32-year-old African-American male.
Digital Object Identifier (DOI)
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